Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human [Treatment of infantile spasms with long-term low dose ACTH]. 1327015

1992

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human [Treatment of infantile spasms with long-term low dose ACTH]. 1327015

1992

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human We hypothesized that ACTH-induced hypertension in the rat is characterized by increased EPO production. 15110907

2004

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human We hypothesized that ACTH-induced hypertension in the rat is characterized by increased EPO production. 15110907

2004

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat. 11071300

2000

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat. 11071300

2000

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human Vasodilator prostanoids and ACTH-dependent hypertension. 6135010

1983

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human Vasodilator prostanoids and ACTH-dependent hypertension. 6135010

1983

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human Thus, NAC partially prevented but did not reverse ACTH-induced hypertension. 16546835

2006

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human Thus, NAC partially prevented but did not reverse ACTH-induced hypertension. 16546835

2006

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human This result indicates that the cardiac glycoside binding site of the alpha1 isoform can also mediate ACTH-induced hypertension. 16243970

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human This result indicates that the cardiac glycoside binding site of the alpha1 isoform can also mediate ACTH-induced hypertension. 16243970

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human These studies suggest that an ACTH-dependent steroid rather than aldosterone, 18-OH-DOC, or DOC may be the cause of the hypertension in this patient. 323586

1977

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human These studies suggest that an ACTH-dependent steroid rather than aldosterone, 18-OH-DOC, or DOC may be the cause of the hypertension in this patient. 323586

1977

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH-induced hypertension in this patient. 187612

1976

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH-induced hypertension in this patient. 187612

1976

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human The role of this increased pressor responsiveness in ACTH/steroid-induced hypertension remains to be determined. 1321309

1992

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human The role of this increased pressor responsiveness in ACTH/steroid-induced hypertension remains to be determined. 1321309

1992

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human The role of the parathyroid glands in adrenocorticotrophin-induced hypertension in the rat. 10513829

1999

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human The role of the parathyroid glands in adrenocorticotrophin-induced hypertension in the rat. 10513829

1999

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. 11132610

2000

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. 11132610

2000

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Biomarker CTD_human The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension. 19458537

2009

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension. 19458537

2009

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.400 Therapeutic CTD_human The glucocorticoid receptor is required for experimental adrenocorticotrophic hormone-induced hypertension in mice. 20659135

2010